CELLULAR SENESCENCE: A TRANSLATIONAL PERSPECTIVE

Cellular Senescence: A Translational Perspective

Cellular senescence entails essentially irreversible replicative arrest, apoptosis resistance, fr3622 and frequently acquisition of a pro-inflammatory, tissue-destructive senescence-associated secretory phenotype (SASP).Senescent cells accumulate in various tissues with aging and at sites of pathogenesis in many chronic diseases and conditions.The

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